A non-invasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo(†)

Genetically encoded probes are widely used to visualize cellular processes in vitro and in vivo. Although effective in cultured cells, fluorescent protein tags and reporters are sub-optimal in vivo due to poor tissue penetration and high background signal. Luciferase reporters offer improved signal-...

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Detalles Bibliográficos
Autores principales: Humpton, Timothy J, Hock, Andreas K, Kiourtis, Christos, Donatis, Marco De, Fercoq, Frederic, Nixon, Colin, Bryson, Sheila, Strathdee, Douglas, Carlin, Leo M., Bird, Thomas G., Blyth, Karen, Vousden, Karen H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612476/
https://www.ncbi.nlm.nih.gov/pubmed/35133863
http://dx.doi.org/10.1126/scisignal.abd9099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612476/
https://www.ncbi.nlm.nih.gov/pubmed/35133863
http://dx.doi.org/10.1126/scisignal.abd9099

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