Molecular and Clinical Repercussions of GABA Transporter 1 Variants Gone Amiss: Links to Epilepsy and Developmental Spectrum Disorders

The human γ-aminobutyric acid (GABA) transporter 1 (hGAT-1) is the first member of the solute carrier 6 (SLC6) protein superfamily. GAT-1 (SLC6A1) is one of the main GABA transporters in the central nervous system. Its principal physiological role is retrieving GABA from the synapse into neurons and...

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Detalles Bibliográficos
Autores principales: Fischer, Florian P., Kasture, Ameya S., Hummel, Thomas, Sucic, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612498/
https://www.ncbi.nlm.nih.gov/pubmed/35295842
http://dx.doi.org/10.3389/fmolb.2022.834498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612498/
https://www.ncbi.nlm.nih.gov/pubmed/35295842
http://dx.doi.org/10.3389/fmolb.2022.834498

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