Assessing CSF ctDNA to Improve Diagnostic Accuracy and Therapeutic Monitoring in Breast Cancer Leptomeningeal Metastasis

PURPOSE: Cerebrospinal fluid (CSF) cytology is the gold standard diagnostic test for breast cancer leptomeningeal metastasis (BCLM), but has impaired sensitivity, often necessitating repeated lumbar puncture to confirm or refute diagnosis. Further, there is no quantitative response tool to assess re...

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Detalles Bibliográficos
Autores principales: Fitzpatrick, Amanda, Iravani, Marjan, Mills, Adam, Childs, Lucy, Alaguthurai, Thanussuyah, Clifford, Angela, Garcia-Murillas, Isaac, Van Laere, Steven, Dirix, Luc, Harries, Mark, Okines, Alicia, Turner, Nicholas C., Haider, Syed, Tutt, Andrew N.J., Isacke, Clare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Precision Medicine and Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612501/
https://www.ncbi.nlm.nih.gov/pubmed/34921020
http://dx.doi.org/10.1158/1078-0432.CCR-21-3017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612501/
https://www.ncbi.nlm.nih.gov/pubmed/34921020
http://dx.doi.org/10.1158/1078-0432.CCR-21-3017

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