New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination

Oligodendrocytes that survive demyelination can remyelinate, including in Multiple Sclerosis (MS), but how they do so is unclear. Here, using zebrafish, we found that surviving oligodendrocytes make few new sheaths and frequently mistarget new myelin to neuronal cell bodies, a pathology we also foun...

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Detalles Bibliográficos
Autores principales: Neely, Sarah A, Williamson, Jill M, Klingseisen, Anna, Zoupi, Lida, Early, Jason J, Williams, Anna, Lyons, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612594/
https://www.ncbi.nlm.nih.gov/pubmed/35165460
http://dx.doi.org/10.1038/s41593-021-01009-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612594/
https://www.ncbi.nlm.nih.gov/pubmed/35165460
http://dx.doi.org/10.1038/s41593-021-01009-x

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