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New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination
Oligodendrocytes that survive demyelination can remyelinate, including in Multiple Sclerosis (MS), but how they do so is unclear. Here, using zebrafish, we found that surviving oligodendrocytes make few new sheaths and frequently mistarget new myelin to neuronal cell bodies, a pathology we also foun...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612594/ https://www.ncbi.nlm.nih.gov/pubmed/35165460 http://dx.doi.org/10.1038/s41593-021-01009-x |