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A dose-finding design for dual-agent trials with patient-specific doses for one agent with application to an opiate detoxification trial
There is a growing interest in early phase dose-finding clinical trials studying combinations of several treatments. While the majority of dose finding designs for such setting were proposed for oncology trials, the corresponding designs are also essential in other therapeutic areas. Furthermore, th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612599/ https://www.ncbi.nlm.nih.gov/pubmed/34891221 http://dx.doi.org/10.1002/pst.2181 |