Cargando…

Treatment allocation strategies for umbrella trials in the presence of multiple biomarkers: A comparison of methods

Umbrella trials are an innovative trial design where different treatments are matched with subtypes of a disease, with the matching typically based on a set of biomarkers. Consequently, when patients can be positive for more than one biomarker, they may be eligible for multiple treatment arms. In pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ouma, Luke Ondijo, Grayling, Michael J., Zheng, Haiyan, Wason, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612600/
https://www.ncbi.nlm.nih.gov/pubmed/33759353
http://dx.doi.org/10.1002/pst.2119