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Treatment allocation strategies for umbrella trials in the presence of multiple biomarkers: A comparison of methods
Umbrella trials are an innovative trial design where different treatments are matched with subtypes of a disease, with the matching typically based on a set of biomarkers. Consequently, when patients can be positive for more than one biomarker, they may be eligible for multiple treatment arms. In pr...
Autores principales: | Ouma, Luke Ondijo, Grayling, Michael J., Zheng, Haiyan, Wason, James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612600/ https://www.ncbi.nlm.nih.gov/pubmed/33759353 http://dx.doi.org/10.1002/pst.2119 |
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