Collateral-resistance to estrogen and HER-activated growth is associated with modified AKT, ERα, and cell-cycle signaling in a breast cancer model

AIM: A model of progressively endocrine-resistant breast cancer was investigated to identify changes that can occur in signaling pathways after endocrine manipulation. METHODS: The MCF7 breast cancer model is sensitive to estrogens and anti-estrogens while variant lines previously derived from wild-...

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Detalles Bibliográficos
Autores principales: Moore, Kate M., Cerqueira, Vera, MacLeod, Kenneth G., Mullen, Peter, Hayward, Richard L., Green, Simon, Harrison, David J., Cameron, David A., Langdon, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Exploration 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612628/
https://www.ncbi.nlm.nih.gov/pubmed/35441158
http://dx.doi.org/10.37349/etat.2022.00074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612628/
https://www.ncbi.nlm.nih.gov/pubmed/35441158
http://dx.doi.org/10.37349/etat.2022.00074

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