Cargando…
Sample size estimation using a latent variable model for mixed outcome co‐primary, multiple primary and composite endpoints
Mixed outcome endpoints that combine multiple continuous and discrete components are often employed as primary outcome measures in clinical trials. These may be in the form of co‐primary endpoints, which conclude effectiveness overall if an effect occurs in all of the components, or multiple primary...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612654/ https://www.ncbi.nlm.nih.gov/pubmed/35199380 http://dx.doi.org/10.1002/sim.9356 |