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Sample size estimation using a latent variable model for mixed outcome co‐primary, multiple primary and composite endpoints

Mixed outcome endpoints that combine multiple continuous and discrete components are often employed as primary outcome measures in clinical trials. These may be in the form of co‐primary endpoints, which conclude effectiveness overall if an effect occurs in all of the components, or multiple primary...

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Detalles Bibliográficos
Autores principales: McMenamin, Martina E., Barrett, Jessica K., Berglind, Anna, Wason, James M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612654/
https://www.ncbi.nlm.nih.gov/pubmed/35199380
http://dx.doi.org/10.1002/sim.9356