Structure and mechanism of the methyltransferase ribozyme MTR1

RNA-catalysed RNA methylation was recently shown to be part of the catalytic repertoire of ribozymes. The methyltransferase ribozyme MTR1 catalyses the site-specific synthesis of 1-methyladenosine (m(1)A) in RNA, using O(6)-methylguanine (m(6)G) as methyl group donor. Here we report the crystal stru...

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Detalles Bibliográficos
Autores principales: Scheitl, Carolin P.M., Mieczkowski, Mateusz, Schindelin, Hermann, Höbartner, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612680/
https://www.ncbi.nlm.nih.gov/pubmed/35301481
http://dx.doi.org/10.1038/s41589-022-00976-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612680/
https://www.ncbi.nlm.nih.gov/pubmed/35301481
http://dx.doi.org/10.1038/s41589-022-00976-x

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