Elucidating the mechanisms underlying protein conformational switching using NMR spectroscopy

How proteins switch between various ligand-free and ligand-bound structures has been a key biophysical question ever since the postulation of the Monod-Wyman-Changeux and Koshland-Nemethy-Filmer models over six decades ago. The ability of NMR spectroscopy to provide structural and kinetic informatio...

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Detalles Bibliográficos
Autores principales: Jain, Shefali, Sekhar, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612731/
https://www.ncbi.nlm.nih.gov/pubmed/35586549
http://dx.doi.org/10.1016/j.jmro.2022.100034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612731/
https://www.ncbi.nlm.nih.gov/pubmed/35586549
http://dx.doi.org/10.1016/j.jmro.2022.100034

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