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Elucidating the mechanisms underlying protein conformational switching using NMR spectroscopy

How proteins switch between various ligand-free and ligand-bound structures has been a key biophysical question ever since the postulation of the Monod-Wyman-Changeux and Koshland-Nemethy-Filmer models over six decades ago. The ability of NMR spectroscopy to provide structural and kinetic informatio...

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Detalles Bibliográficos
Autores principales:	Jain, Shefali, Sekhar, Ashok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612731/ https://www.ncbi.nlm.nih.gov/pubmed/35586549 http://dx.doi.org/10.1016/j.jmro.2022.100034

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