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Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors
G-protein-coupled receptors (GPCRs), also known as seven transmembrane receptors (7TMRs), typically interact with two distinct signal-transducers, i.e., G proteins and β-arrestins (βarrs). Interestingly, there are some non-canonical 7TMRs that lack G protein coupling but interact with barrs, althoug...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612807/ https://www.ncbi.nlm.nih.gov/pubmed/34582793 http://dx.doi.org/10.1016/j.molcel.2021.09.007 |