An innate IL-25-ILC2-MDSC axis creates a cancer-permissive microenvironment for Apc-mutation-driven intestinal tumorigenesis

Interleukin-25 and group 2 innate lymphoid cells (ILC2s) defend the host against intestinal helminth infection, and are associated with inappropriate allergic reactions. IL-33-activated ILC2s were previously found to augment protective tissue-specific pancreatic cancer immunity. Here, we showed that...

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Detalles Bibliográficos
Autores principales: Jou, Eric, Rodriguez-Rodriguez, Noe, Ferreira, Ana-Carolina F., Jolin, Helen E., Clark, Paula A., Sawmynaden, Kovilen, Ko, Michelle, Murphy, Jane E., Mannion, Jonathan, Ward, Christopher, Matthews, David J., Buczacki, Simon J. A., McKenzie, Andrew N. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612821/
https://www.ncbi.nlm.nih.gov/pubmed/35658010
http://dx.doi.org/10.1126/sciimmunol.abn0175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612821/
https://www.ncbi.nlm.nih.gov/pubmed/35658010
http://dx.doi.org/10.1126/sciimmunol.abn0175

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