Tracking mutation and drug-driven alterations of oncokinase conformations

Numerous kinases act as central nodes of cellular signaling networks. As such, many of these enzymes function as molecular switches for coordinating spatiotemporal signal transmission. Typically, it is the compartmentalized phosphorylation of protein substrates which relays the transient input signa...

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Detalles Bibliográficos
Autores principales: Feichtner, Andreas, Kugler, Valentina, Schwaighofer, Selina, Nuener, Thomas, Fleischmann, Jakob, Stefan, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612828/
https://www.ncbi.nlm.nih.gov/pubmed/35677701
http://dx.doi.org/10.1007/s12254-021-00790-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612828/
https://www.ncbi.nlm.nih.gov/pubmed/35677701
http://dx.doi.org/10.1007/s12254-021-00790-6

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