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Risk of immune reconstitution inflammatory syndrome with integrase inhibitors versus other classes of antiretrovirals: a systematic review and meta-analysis of randomised trials

BACKGROUND: Integrase strand transfer inhibitors (InSTIs) decrease HIV plasma viral load faster than other antiretroviral classes. More rapid viral load decline has been associated with higher risk of immune reconstitution inflammatory syndrome (IRIS). There are conflicting reports on the associatio...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Hohlfeld, Ameer, Namale, Phiona, Meintjes, Graeme, Maartens, Gary, Engel, Mark E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612870/
https://www.ncbi.nlm.nih.gov/pubmed/35175970
http://dx.doi.org/10.1097/QAI.0000000000002937