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Baseline IL-6 is a biomarker for unfavorable tuberculosis treatment outcomes: a multi-site discovery and validation study

BACKGROUND: Biomarkers of unfavorable tuberculosis treatment outcomes are needed to accelerate new drug and regimen development. Whether plasma cytokine levels can predict unfavorable tuberculosis treatment outcomes is unclear. METHODS: We identified and internally validated the association between...

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Detalles Bibliográficos
Autores principales: Gupte, Akshay N., Kumar, Pavan, Araújo-Pereira, Mariana, Kulkarni, Vandana, Paradkar, Mandar, Pradhan, Neeta, Menon, Pradeep, Darasini, Padmapriya, Hanna, Luke-Elizabeth, Shivakumar, Shri Vijay Bala Yogendra, Rockwood, Neesha, Bruyn, Elsa Du, Karyakarte, Rajesh, Gaikwad, Sanjay, Bollinger, Robert, Golub, Jonathan, Gupte, Nikhil, Viswanathan, Vijay, Wilkinson, Robert J., Mave, Vidya, Babu, Subash, Kornfeld, Hardy, Andrade, Bruno B., Gupta, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612881/
https://www.ncbi.nlm.nih.gov/pubmed/34711538
http://dx.doi.org/10.1183/13993003.00905-2021