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Mesp1 controls the chromatin and enhancer landscapes essential for spatiotemporal patterning of early cardiovascular progenitors

The mammalian heart arises from various populations of Mesp1-expressing cardiovascular progenitors (CPs) that are specified during the early stages of gastrulation. Mesp1 is a transcription factor (TF) that acts as a master regulator of CP specification and differentiation. However, how Mesp1 regula...

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Detalles Bibliográficos
Autores principales: Lin, Xionghui, Swedlund, Benjamin, Ton, Mai-Linh N., Ghazanfar, Shila, Guibentif, Carolina, Paulissen, Catherine, Baudelet, Elodie, Plaindoux, Elise, Achouri, Younes, Calonne, Emilie, Dubois, Christine, Mansfield, William, Zaffran, Stéphane, Marioni, John C., Fuks, Francois, Göttgens, Berthold, Lescroart, Fabienne, Blanpain, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613098/
https://www.ncbi.nlm.nih.gov/pubmed/35817961
http://dx.doi.org/10.1038/s41556-022-00947-3