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Interaction With the Lipid Membrane Influences Fentanyl Pharmacology

Overdose deaths from fentanyl have reached epidemic proportions in the USA and are increasing worldwide. Fentanyl is a potent opioid agonist that is less well reversed by naloxone than morphine. Due to fentanyl’s high lipophilicity and elongated structure we hypothesised that its unusual pharmacolog...

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Detalles Bibliográficos
Autores principales: Sutcliffe, Katy J., Corey, Robin A, Alhosan, Norah, Cavallo, Damiana, Groom, Sam, Santiago, Marina, Bailey, Chris, Charlton, Steven J., Sessions, Richard B., Henderson, Graeme, Kelly, Eamonn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613138/
https://www.ncbi.nlm.nih.gov/pubmed/35909438
http://dx.doi.org/10.3389/adar.2022.10280