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Photocaged 5′ cap analogues for optical control of mRNA translation in cells

The translation of messenger RNA (mRNA) is a fundamental process in gene expression, and control of translation is important to regulate protein synthesis in cells. The primary hallmark of eukaryotic mRNAs is their 5′ cap, whose molecular contacts to the eukaryotic translation initiation factor eIF4...

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Detalles Bibliográficos
Autores principales: Klöcker, Nils, Weissenboeck, Florian P., van Dülmen, Melissa, Špaček, Petr, Hüwel, Sabine, Rentmeister, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613264/
https://www.ncbi.nlm.nih.gov/pubmed/35725774
http://dx.doi.org/10.1038/s41557-022-00972-7