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Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover

Focal adhesions are multifunctional organelles that couple cell-matrix adhesion to cytoskeletal force transmission and signaling and to steer cell migration and collective cell behavior. Whereas proteomic changes at focal adhesions are well understood, little is known about signaling lipids in focal...

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Detalles Bibliográficos
Autores principales: Posor, York, Kampyli, Charis, Bilanges, Benoit, Ganguli, Sushila, Koch, Philipp A., Wallroth, Alexander, Morelli, Daniele, Jenkins, Michalina, Alliouachene, Samira, Deltcheva, Elitza, Baum, Buzz, Haucke, Volker, Vanhaesebroeck, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613278/
https://www.ncbi.nlm.nih.gov/pubmed/35809565
http://dx.doi.org/10.1016/j.devcel.2022.06.011