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Proteasome-dependent truncation of the negative heterochromatin regulator Epe1 mediates antifungal resistance
Epe1 histone demethylase restricts H3K9-methylation-dependent heterochromatin, preventing it from spreading over, and silencing, gene-containing regions in fission yeast. External stress induces an adaptive response allowing heterochromatin island formation that confers resistance on surviving wild-...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613290/ https://www.ncbi.nlm.nih.gov/pubmed/35879419 http://dx.doi.org/10.1038/s41594-022-00801-y |