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Proteasome-dependent truncation of the negative heterochromatin regulator Epe1 mediates antifungal resistance

Epe1 histone demethylase restricts H3K9-methylation-dependent heterochromatin, preventing it from spreading over, and silencing, gene-containing regions in fission yeast. External stress induces an adaptive response allowing heterochromatin island formation that confers resistance on surviving wild-...

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Detalles Bibliográficos
Autores principales: Yaseen, Imtiyaz, White, Sharon A., Torres-Garcia, Sito, Spanos, Christos, Lafos, Marcel, Gaberdiel, Elisabeth, Yeboah, Rebecca, Karoui, Meriem El, Rappsilber, Juri, Pidoux, Alison L., Allshire, Robin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613290/
https://www.ncbi.nlm.nih.gov/pubmed/35879419
http://dx.doi.org/10.1038/s41594-022-00801-y