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Transcriptomic signatures induced by the Ebola virus vaccine rVSVΔG-ZEBOV-GP in adult cohorts in Europe, Africa, and North America: a molecular biomarker study

BACKGROUND: A recombinant vesicular stomatitis virus vector expressing the Zaire Ebola virus glycoprotein (rVSVΔG-ZEBOV-GP) vaccine has been reported as safe, immunogenic, and highly protective in a ring vaccination trial. We aimed to identify transcriptomic immune response biomarker signatures indu...

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Detalles Bibliográficos
Autores principales: Vianello, Eleonora, Gonzalez-Dias, Patricia, van Veen, Suzanne, Engele, Carmen G, Quinten, Edwin, Monath, Thomas P, Medaglini, Donata, Santoro, Francesco, Huttner, Angela, Dubey, Sheri, Eichberg, Michael, Ndungu, Francis M, Kremsner, Peter G, Essone, Paulin N, Agnandji, Selidji Todagbe, Siegrist, Claire-Anne, Nakaya, Helder I, Ottenhoff, Tom H M, Haks, Mariëlle C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613316/
https://www.ncbi.nlm.nih.gov/pubmed/35544042
http://dx.doi.org/10.1016/S2666-5247(21)00235-4