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Composite vector formulation for multiple siRNA delivery as a host targeting antiviral in a cell culture model of hepatitis C virus (HCV) infection†

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and cancer worldwide. RNA interference (RNAi)-based gene therapies have emerged recently as a promising tool to treat chronic viral infections. Indeed, small interfering RNAs (siRNAs) provide an opportunity to target host fa...

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Detalles Bibliográficos
Autores principales: Crouchet, E., Saad, R., Affolter-Zbaraszczuk, C., Ogier, J., Baumert, T. F., Schuster, C., Meyer, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613424/
https://www.ncbi.nlm.nih.gov/pubmed/32263854
http://dx.doi.org/10.1039/c6tb01718e