Epstein–Barr virus and malaria upregulate AID and APOBEC3 enzymes, but only AID seems to play a major mutagenic role in Burkitt lymphoma

Endemic Burkitt lymphoma (eBL) is characterized by an oncogenic IGH/c‐MYC translocation and Epstein–Barr virus (EBV) positivity, and is epidemiologically linked to Plasmodium falciparum malaria. Both EBV and malaria are thought to contribute to eBL by inducing the expression of activation‐induced cy...

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Detalles Bibliográficos
Autores principales: Summerauer, Andrea M., Jäggi, Vera, Ogwang, Rodney, Traxel, Sabrina, Colombo, Lorenzo, Amundsen, Eivind, Eyer, Tatjana, Subramanian, Bibin, Fehr, Jan, Mantel, Pierre‐Yves, Idro, Richard, Bürgler, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Immunity to infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613445/
https://www.ncbi.nlm.nih.gov/pubmed/35503749
http://dx.doi.org/10.1002/eji.202249820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613445/
https://www.ncbi.nlm.nih.gov/pubmed/35503749
http://dx.doi.org/10.1002/eji.202249820

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