Cargando…

Short peptide pharmacophores developed from protein phosphatase-1 disrupting peptides (PDPs)

PP1 is a major phosphoserine/threonine-specific phosphatase that is involved in diseases such as heart insufficiency and diabetes. PP1-disrupting peptides (PDPs) are selective modulators of PP1 activity that release its catalytic subunit, which then dephosphorylates nearby substrates. Recently, PDPs...

Descripción completa

Detalles Bibliográficos
Autores principales: Fontanillo, Miriam, Trebacz, Malgorzata, Reinkemeier, Christopher D., Huerta, Daniela Avilés, Uhrig, Ulrike, Sehr, Peter, Köhn, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613447/
https://www.ncbi.nlm.nih.gov/pubmed/35525109
http://dx.doi.org/10.1016/j.bmc.2022.116785