Genome-based discovery and total synthesis of janustatins, potent cytotoxins from a plant-associated bacterium

Host-associated bacteria are increasingly recognized as underexplored sources of bioactive natural products with unprecedented chemical scaffolds. A recently identified example is the plant root-associated marine bacterium Gynuella sunshinyii of the chemically underexplored order Oceanospirillales....

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Detalles Bibliográficos
Autores principales: Ueoka, Reiko, Sondermann, Philipp, Leopold-Messer, Stefan, Liu, Yizhou, Suo, Rei, Bhushan, Agneya, Vadakumchery, Lida, Greczmiel, Ute, Yashiroda, Yoko, Kimura, Hiromi, Nishimura, Shinichi, Hoshikawa, Yojiro, Yoshida, Minoru, Oxenius, Annette, Matsunaga, Shigeki, Williamson, R. Thomas, Carreira, Erick M., Piel, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613652/
https://www.ncbi.nlm.nih.gov/pubmed/36064972
http://dx.doi.org/10.1038/s41557-022-01020-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613652/
https://www.ncbi.nlm.nih.gov/pubmed/36064972
http://dx.doi.org/10.1038/s41557-022-01020-0

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