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Uterine natural killer cells ace an “A” in education: NKG2A sets up crucial functions at the maternal-fetal interface

I argue here that reproduction was a driving force in the evolution of NK-cell education, which is set by interactions between inhibitory receptors and self MHC. Maternal lymphocytes also interact with allogeneic MHC on fetal trophoblast cells. How the maternal immune system accommodates the semi-al...

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Detalles Bibliográficos
Autor principal: Colucci, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613701/
https://www.ncbi.nlm.nih.gov/pubmed/36192118
http://dx.doi.org/10.4049/jimmunol.2200384