Development and validation of an LC-MS/MS methodology for the quantification of thyroid hormones in dko MCT8/OATP1C1 mouse brain

The Allan-Herndon Dudley Syndrome (AHDS) is a rare disease caused by the progressive loss of monocarboxylate transporter 8 (MCT8). In patients with AHDS, the absence of MCT8 impairs transport of thyroid hormones (TH) through the blood brain barrier, leading to a central state of TH deficiency. In mi...

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Detalles Bibliográficos
Autores principales: De Angelis, Meri, Maity-Kumar, Gandhari, Schriever, Sonja C., Kozlova, Elena V., Müller, Timo D., Pfluger, Paul T., Curras-Collazo, Margarita C., Schramm, Karl-Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613747/
https://www.ncbi.nlm.nih.gov/pubmed/36152487
http://dx.doi.org/10.1016/j.jpba.2022.115038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613747/
https://www.ncbi.nlm.nih.gov/pubmed/36152487
http://dx.doi.org/10.1016/j.jpba.2022.115038

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