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Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment

A holistic understanding of tissue and organ structure and function requires the detection of molecular constituents in their original three-dimensional (3D) context. Imaging mass cytometry (IMC) enables simultaneous detection of up to 40 antigens and transcripts using metal-tagged antibodies but ha...

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Detalles Bibliográficos
Autores principales: Kuett, Laura, Catena, Raúl, Özcan, Alaz, Plüss, Alex, Schraml, Peter, Moch, Holger, de Souza, Natalie, Bodenmiller, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613779/
https://www.ncbi.nlm.nih.gov/pubmed/35121992
http://dx.doi.org/10.1038/s43018-021-00301-w