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The benefits of covariate adjustment for adaptive multi-arm designs

Covariate adjustment via a regression approach is known to increase the precision of statistical inference when fixed trial designs are employed in randomized controlled studies. When an adaptive multi-arm design is employed with the ability to select treatments, it is unclear how covariate adjustme...

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Detalles Bibliográficos
Autores principales: Lee, Kim May, Robertson, David S., Jaki, Thomas, Emsley, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613816/
https://www.ncbi.nlm.nih.gov/pubmed/35876412
http://dx.doi.org/10.1177/09622802221114544