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Dietary Restriction and Medical Therapy Drives PPARα-Regulated Improvements in Early Diabetic Kidney Disease in Male Rats

The attenuation of diabetic kidney disease (DKD) by metabolic surgery is enhanced by pharmacotherapy promoting renal fatty acid oxidation (FAO). Using the Zucker Diabetic Fatty and Zucker Diabetic Sprague Dawley rat models of DKD, we conducted studies to determine if these effects could be replicate...

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Detalles Bibliográficos
Autores principales: Martin, William P., Nair, Meera, Chuah, Yeong H.D., Malmodin, Daniel, Pedersen, Anders, Abrahamsson, Sanna, Hutter, Michaela, Abdelaal, Mahmoud, Elliott, Jessie A., Fearon, Naomi, Eckhardt, Hans, Godson, Catherine, Brennan, Eoin P., Fändriks, Lars, le Roux, Carel W., Docherty, Neil G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613831/
https://www.ncbi.nlm.nih.gov/pubmed/36259366
http://dx.doi.org/10.1042/CS20220205