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Dietary Restriction and Medical Therapy Drives PPARα-Regulated Improvements in Early Diabetic Kidney Disease in Male Rats
The attenuation of diabetic kidney disease (DKD) by metabolic surgery is enhanced by pharmacotherapy promoting renal fatty acid oxidation (FAO). Using the Zucker Diabetic Fatty and Zucker Diabetic Sprague Dawley rat models of DKD, we conducted studies to determine if these effects could be replicate...
Autores principales: | Martin, William P., Nair, Meera, Chuah, Yeong H.D., Malmodin, Daniel, Pedersen, Anders, Abrahamsson, Sanna, Hutter, Michaela, Abdelaal, Mahmoud, Elliott, Jessie A., Fearon, Naomi, Eckhardt, Hans, Godson, Catherine, Brennan, Eoin P., Fändriks, Lars, le Roux, Carel W., Docherty, Neil G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613831/ https://www.ncbi.nlm.nih.gov/pubmed/36259366 http://dx.doi.org/10.1042/CS20220205 |
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