An immune dysfunction score for stratification of patients with acute infection based on whole blood gene expression

Dysregulated host responses to infection can lead to organ dysfunction and sepsis, causing millions of global deaths each year. To alleviate this burden, improved prognostication and biomarkers of response are urgently needed. We investigated the use of whole blood transcriptomics for stratification...

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Detalles Bibliográficos
Autores principales: Cano-Gamez, Eddie, Burnham, Katie L, Goh, Cyndi, Allcock, Alice, Malick, Zunaira H., Overend, Lauren, Kwok, Andrew, Smith, David A., Peters-Sengers, Hessel, Antcliffe, David, McKechnie, Stuart, Scicluna, Brendon P., van der Poll, Tom, Gordon, Anthony C., Hinds, Charles J., Davenport, Emma E., Knight, Julian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613832/
https://www.ncbi.nlm.nih.gov/pubmed/36322631
http://dx.doi.org/10.1126/scitranslmed.abq4433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613832/
https://www.ncbi.nlm.nih.gov/pubmed/36322631
http://dx.doi.org/10.1126/scitranslmed.abq4433

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