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An immune dysfunction score for stratification of patients with acute infection based on whole blood gene expression
Dysregulated host responses to infection can lead to organ dysfunction and sepsis, causing millions of global deaths each year. To alleviate this burden, improved prognostication and biomarkers of response are urgently needed. We investigated the use of whole blood transcriptomics for stratification...
Autores principales: | Cano-Gamez, Eddie, Burnham, Katie L, Goh, Cyndi, Allcock, Alice, Malick, Zunaira H., Overend, Lauren, Kwok, Andrew, Smith, David A., Peters-Sengers, Hessel, Antcliffe, David, McKechnie, Stuart, Scicluna, Brendon P., van der Poll, Tom, Gordon, Anthony C., Hinds, Charles J., Davenport, Emma E., Knight, Julian C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613832/ https://www.ncbi.nlm.nih.gov/pubmed/36322631 http://dx.doi.org/10.1126/scitranslmed.abq4433 |
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