Mucin O-glycans are natural inhibitors of Candida albicans pathogenicity

Mucins are large gel-forming polymers inside the mucus barrier that inhibit the yeast to hyphal transition of Candida albicans, a key virulence trait of this important human fungal pathogen. However, the molecular motifs in mucins that inhibit filamentation remain unclear, despite their potential fo...

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Detalles Bibliográficos
Autores principales: Takagi, Julie, Aoki, Kazuhiro, Turner, Bradley S., Lamont, Sabrina, Lehoux, Sylvain, Kavanaugh, Nicole, Gulati, Megha, Arevalo, Ashley Valle, Lawrence, Travis J., Kim, Colin Y., Bakshi, Bhavya, Ishihara, Mayumi, Nobile, Clarissa J., Cummings, Richard D., Wozniak, Daniel, Tiemeyer, Michael, Hevey, Rachel, Ribbeck, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613833/
https://www.ncbi.nlm.nih.gov/pubmed/35668191
http://dx.doi.org/10.1038/s41589-022-01035-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613833/
https://www.ncbi.nlm.nih.gov/pubmed/35668191
http://dx.doi.org/10.1038/s41589-022-01035-1

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