Diene Incorporation by a Dehydratase Domain Variant in Modular Polyketide Synthases

Modular polyketide synthases (PKSs) are biosynthetic assembly lines that construct structurally diverse natural products with wide-ranging applications in medicine and agriculture. Various mechanisms contribute to structural diversification during PKS-mediated chain assembly, including dehydratase (...

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Detalles Bibliográficos
Autores principales: Hobson, Christian, Jenner, Matthew, Jian, Xinyun, Griffiths, Daniel, Roberts, Douglas M., Rey-Carrizo, Matias, Challis, Gregory L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613849/
https://www.ncbi.nlm.nih.gov/pubmed/36109649
http://dx.doi.org/10.1038/s41589-022-01127-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613849/
https://www.ncbi.nlm.nih.gov/pubmed/36109649
http://dx.doi.org/10.1038/s41589-022-01127-y

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