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Diene Incorporation by a Dehydratase Domain Variant in Modular Polyketide Synthases

Modular polyketide synthases (PKSs) are biosynthetic assembly lines that construct structurally diverse natural products with wide-ranging applications in medicine and agriculture. Various mechanisms contribute to structural diversification during PKS-mediated chain assembly, including dehydratase (...

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Detalles Bibliográficos
Autores principales:	Hobson, Christian, Jenner, Matthew, Jian, Xinyun, Griffiths, Daniel, Roberts, Douglas M., Rey-Carrizo, Matias, Challis, Gregory L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613849/ https://www.ncbi.nlm.nih.gov/pubmed/36109649 http://dx.doi.org/10.1038/s41589-022-01127-y

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