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Two-stage penalized regression screening to detect biomarker-treatment interactions in randomized clinical trials
High-dimensional biomarkers such as genomics are increasingly being measured in randomized clinical trials. Consequently, there is a growing interest in developing methods that improve the power to detect biomarker–treatment interactions. We adapt recently proposed two-stage interaction detecting pr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613856/ https://www.ncbi.nlm.nih.gov/pubmed/33448327 http://dx.doi.org/10.1111/biom.13424 |