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ABCB1 variants and sex affect serotonin transporter occupancy in the brain

Strategies to personalize psychopharmacological treatment promise to improve efficacy and tolerability. We measured serotonin transporter occupancy immediately after infusion of the widely prescribed P-glycoprotein substrate citalopram and assessed to what extent variants of the ABCB1 gene affect dr...

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Detalles Bibliográficos
Autores principales: Silberbauer, Leo R., Rischka, Lucas, Vraka, Chrysoula, Hartmann, Annette M., Godbersen, Godber Mathis, Philippe, Cécile, Pacher, Daniel, Nics, Lukas, Klöbl, Manfred, Unterholzner, Jakob, Stimpfl, Thomas, Wadsak, Wolfgang, Hahn, Andreas, Hacker, Marcus, Rujescu, Dan, Kasper, Siegfried, Lanzenberger, Rupert, Gryglewski, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613909/
https://www.ncbi.nlm.nih.gov/pubmed/36071112
http://dx.doi.org/10.1038/s41380-022-01733-1