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ABCB1 variants and sex affect serotonin transporter occupancy in the brain
Strategies to personalize psychopharmacological treatment promise to improve efficacy and tolerability. We measured serotonin transporter occupancy immediately after infusion of the widely prescribed P-glycoprotein substrate citalopram and assessed to what extent variants of the ABCB1 gene affect dr...
Autores principales: | Silberbauer, Leo R., Rischka, Lucas, Vraka, Chrysoula, Hartmann, Annette M., Godbersen, Godber Mathis, Philippe, Cécile, Pacher, Daniel, Nics, Lukas, Klöbl, Manfred, Unterholzner, Jakob, Stimpfl, Thomas, Wadsak, Wolfgang, Hahn, Andreas, Hacker, Marcus, Rujescu, Dan, Kasper, Siegfried, Lanzenberger, Rupert, Gryglewski, Gregor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613909/ https://www.ncbi.nlm.nih.gov/pubmed/36071112 http://dx.doi.org/10.1038/s41380-022-01733-1 |
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