Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals

Ferroptosis is a type of cell death caused by radical-driven lipid peroxidation, leading to membrane damage and rupture. Here we show that enzymatically produced sulfane sulfur (S(0)) species, specifically hydropersulfides, scavenge endogenously generated free radicals and, thereby, suppress lipid p...

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Detalles Bibliográficos
Autores principales: Barayeu, Uladzimir, Schilling, Danny, Eid, Mohammad, Xavier da Silva, Thamara Nishida, Schlicker, Lisa, Mitreska, Nikolina, Zapp, Christopher, Gräter, Frauke, Miller, Aubry K., Kappl, Reinhard, Schulze, Almut, Friedmann Angeli, José Pedro, Dick, Tobias P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613997/
https://www.ncbi.nlm.nih.gov/pubmed/36109647
http://dx.doi.org/10.1038/s41589-022-01145-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613997/
https://www.ncbi.nlm.nih.gov/pubmed/36109647
http://dx.doi.org/10.1038/s41589-022-01145-w

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