An αvβ3 integrin checkpoint is critical for efficient T(H)2 cytokine polarisation and potentiating antigen-specific immunity

Naïve CD4(+) T lymphocytes initially undergo antigen-specific activation to promote a broad-spectrum response before adopting bespoke cytokine expression profiles shaped by intercellular microenvironmental cues, resulting in pathogen-focussed modular cytokine responses. Interleukin (IL)-4-induced Ga...

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Detalles Bibliográficos
Autores principales: Szeto, Aydan C. H., Ferreira, Ana C. F., Mannion, Jonathan, Clark, Paula A., Sivasubramaniam, Meera, Heycock, Morgan W. D., Crisp, Alastair, Jolin, Helen E., Kozik, Patrycja, Knolle, Martin D., McKenzie, Andrew N. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614022/
https://www.ncbi.nlm.nih.gov/pubmed/36550322
http://dx.doi.org/10.1038/s41590-022-01378-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614022/
https://www.ncbi.nlm.nih.gov/pubmed/36550322
http://dx.doi.org/10.1038/s41590-022-01378-w

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