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Three-dimensional Imaging Reveals Immune-driven Tumor-associated High Endothelial Venules as a Key Correlate of Tumor Rejection Following Depletion of Regulatory T Cells

High endothelial venules (HEV) are specialized post capillary venules that recruit naïve T cells and B cells into secondary lymphoid organs (SLO) such as lymph nodes (LN). Expansion of HEV networks in SLOs occurs following immune activation to support development of an effective immune response. In...

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Detalles Bibliográficos
Autores principales: Milutinovic, Stefan, Abe, Jun, Jones, Emma, Kelch, Inken, Smart, Kathryn, Lauder, Sarah N., Somerville, Michelle, Ware, Carl, Godkin, Andrew, Stein, Jens V., Bogle, Gib, Gallimore, Awen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614106/
https://www.ncbi.nlm.nih.gov/pubmed/36704666
http://dx.doi.org/10.1158/2767-9764.CRC-21-0123