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Three-dimensional Imaging Reveals Immune-driven Tumor-associated High Endothelial Venules as a Key Correlate of Tumor Rejection Following Depletion of Regulatory T Cells
High endothelial venules (HEV) are specialized post capillary venules that recruit naïve T cells and B cells into secondary lymphoid organs (SLO) such as lymph nodes (LN). Expansion of HEV networks in SLOs occurs following immune activation to support development of an effective immune response. In...
Autores principales: | Milutinovic, Stefan, Abe, Jun, Jones, Emma, Kelch, Inken, Smart, Kathryn, Lauder, Sarah N., Somerville, Michelle, Ware, Carl, Godkin, Andrew, Stein, Jens V., Bogle, Gib, Gallimore, Awen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614106/ https://www.ncbi.nlm.nih.gov/pubmed/36704666 http://dx.doi.org/10.1158/2767-9764.CRC-21-0123 |
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