Cargando…
NOTCH dependent cooperativity between myeloid lineages promotes Langerhans cell histiocytosis pathology
Langerhans cell histiocytosis (LCH) is a potentially fatal neoplasm, characterized by the aberrant differentiation of mononuclear phagocytes, driven by mitogen-activated protein kinase pathway activation. LCH cells may trigger destructive pathology yet remain in precarious state, finely balanced bet...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614120/ https://www.ncbi.nlm.nih.gov/pubmed/36525505 http://dx.doi.org/10.1126/sciimmunol.add3330 |