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NOTCH dependent cooperativity between myeloid lineages promotes Langerhans cell histiocytosis pathology

Langerhans cell histiocytosis (LCH) is a potentially fatal neoplasm, characterized by the aberrant differentiation of mononuclear phagocytes, driven by mitogen-activated protein kinase pathway activation. LCH cells may trigger destructive pathology yet remain in precarious state, finely balanced bet...

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Detalles Bibliográficos
Autores principales: Kvedaraite, Egle, Milne, Paul, Khalilnezhad, Ahad, Chevrier, Marion, Sethi, Raman, Lee, Hong Kai, Hagey, Daniel W., von Bahr Greenwood, Tatiana, Mouratidou, Natalia, Jädersten, Martin, Lee, Nicole Yee Shin, Minnerup, Lara, Yingrou, Tan, Dutertre, Charles-Antoine, Benac, Nathan, Hwang, You Yi, Lum, Josephine, Loh, Amos Hong Pheng, Jansson, Jessica, Teng, Karen Wei Weng, Khalilnezhad, Shabnam, Weili, Xu, Resteu, Anastasia, Liang, Tey Hong, Guan, Ng Lai, Larbi, Anis, Howland, Shanshan Wu, Arnell, Henrik, Andaloussi, Samir EL, Braier, Jorge, Rassidakis, Georgios, Galluzzo, Laura, Dzionek, Andrzej, Henter, Jan-Inge, Chen, Jinmiao, Collin, Matthew, Ginhoux, Florent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614120/
https://www.ncbi.nlm.nih.gov/pubmed/36525505
http://dx.doi.org/10.1126/sciimmunol.add3330