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BMP-signaling in the intestinal epithelium drives a critical feedback loop to restrain IL-13-driven tuft cell hyperplasia

The intestinal tract is a common site for different types of infections including viruses, bacteria, and helminths, each requiring specific modes of immune defense. The intestinal epithelium has a pivotal role in both immune initiation and effector stages, which are coordinated by immune-type specif...

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Detalles Bibliográficos
Autores principales: Lindholm, Håvard T., Parmar, Naveen, Drurey, Claire, Poveda, Marta Campillo, Vornewald, Pia, Ostrop, Jenny, Díez-Sanchez, Alberto, Maizels, Rick M., Oudhoff, Menno J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614132/
https://www.ncbi.nlm.nih.gov/pubmed/35559665
http://dx.doi.org/10.1126/sciimmunol.abl6543