LC-MS/MS based detection of circulating proinsulin derived peptides in patients with altered pancreatic beta cell function

Routine immunoassays for insulin and C-peptide have the potential to cross-react with partially processed proinsulin products, although in healthy patients these are present at such low levels that the interference is insignificant. Elevated concentrations of proinsulin and des-31,32 proinsulin aris...

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Detalles Bibliográficos
Autores principales: Foreman, Rachel E, Meek, Claire L, Roberts, Geoffrey P, George, Amy L, Reimann, Frank, Gribble, Fiona M, Kay, Richard G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614196/
https://www.ncbi.nlm.nih.gov/pubmed/36242807
http://dx.doi.org/10.1016/j.jchromb.2022.123482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614196/
https://www.ncbi.nlm.nih.gov/pubmed/36242807
http://dx.doi.org/10.1016/j.jchromb.2022.123482

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