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Uncovering the source of mitochondrial superoxide in pro-inflammatory macrophages: Insights from immunometabolism

Mitochondrial-derived reactive oxygen species are important as antimicrobial agents and redox signals in pro-inflammatory macrophages. Macrophages produce superoxide in response to the TLR4 ligand LPS. However, the mechanism of LPS-induced superoxide generation is not fully understood. Superoxide is...

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Detalles Bibliográficos
Autores principales: Casey, Alva M., Murphy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614207/
https://www.ncbi.nlm.nih.gov/pubmed/35792320
http://dx.doi.org/10.1016/j.bbadis.2022.166481